Circadian Rhythms Modulating Brain Cancer Therapies

Our research focuses on developing innovative chrono-immunotherapy strategies for brain cancers. We investigate how circadian rhythms—24-hour cycles that regulate various (patho)physiological processes—shape tumor biology and immune responses. Circadian rhythms are crucial in cancer as disruptions can promote tumor growth, facilitate immune evasion, and impact treatment outcomes. Our goal is to identify novel therapeutic targets and optimize immunotherapeutic strategies to enhance treatment effectiveness and reduce side effects.